Chapter 2 review
Resilience is a card for when you want more soak in addition to your allies, and usually Guardians will want this for horror soak specifically. If we take Logan Hastings he only has one horror soak, so if you want to keep him around and your investigator has low sanity already (both Daniela and Tommy fit this definition) then it can be a useful alternative. Even if you take Charisma and a second ally with more horror soak (Detective Sherman, or Daniel Jameson on Daniela) then they're still usually valuable enough that you won't want to kill them off - so having completely disposable soak like Resilience is handy.
In terms of alternatives, Stakeout provides horror healing, but it's only one (rather than two soak here) and it comes with the risk of failure. Daniela in particular doesn't like it very much with her low stat. Daniela has further options such as Meat Cleaver and Canteen, but Meat Cleaver takes a precious hand slot and Canteen costs XP (and realistically offers more healing than you need in a scenario). Resilience meanwhile can't fail like Stakeout, it's slotless unlike Meat Cleaver, and it costs no experience unlike Canteen. By far the biggest drawback of Resilience is its 3 resource price tag, but in cheap decks (e.g. your main asset combo is Sledgehammer and Logan) then you can usually afford it - and it's often an asset you only play when you need it as well. The single icon does aid its utility, as usually Guardian decks like willpower icons generally - so even if you don't want to stump up the 3 resource cost at a particular point in time then you can instead commit it to a horror-dealing treachery and see some value that way.
Conclusions: It's a pretty niche card, but not innately binder fodder. Most commonly Daniela likes it because it's a 0 XP soak option that preserves more valuable ally assets and gives a further outlet for In Harm's Way, and with melee weapons her decks can run quite cheaply too to afford it. This frees her up to not need XP for things like Canteen, and so invest in the things she likes a lot (Sledgehammer, Scrape By, upgraded Vicious Blow). Even with Daniela, if you do have any other soak in your deck (e.g. Charisma with a two horror soak ally in addition to Logan) then you might only need a single copy as appropriate hedging vs. the encounter deck. For Tommy, usually the resource price tag puts this out of his reach (given guns are expensive) and he also gets better use out of Stakeout (which gives a clue alongside the horror healing, and so is nice for tempo).