Sadly, I think the good Father is pretty bad, at least as Mystics go.
Firstly, he seems to be missing a stat point (at least compared to the mono-colour + trait template that Mark and Akachi set,).
Although Silas too is missing this point, so perhaps it is deemed that "Blessed" and "Innate" is better than "Tactics" and "Spells", which might be true for Innate, but certainly is not for Blessed.
Compared to Agnes or Akachi, he is considerably weaker. He is missing the 5 willpower, which as we know from Jim is huge, but he is also missing the free damage or the spell charges, both of which are considerably more powerful than his own once-per-game (OPG). Compared to Marie, he lacks the investigation options or bonus actions. He compares more favorably to Jim (the current weakest mystic), but even here he loses out. Jim has more support cards now, and is generally seen to be more of a solo-investigator, and has the any-5-splash. Mateo's low strength means solo can be an issue, as he has very little options for the extra 1 point of damage on 3-health enemies if he can't find his Shriveling.
His unique asset (Codex of Ages), is good if you want to pass a single test, but its expensive, uses a hand-slot, and is especially bad in multiplayer where sealing that Elder Sign for more than 1 or 2 turns hurts the whole group. It has uses, eg, with a big Storm of Spirits play, or a Double or Nothing, but these are pretty situational. Combined with his OPG, which can only trigger on a tentacle, and you have two very niche abilities, neither of which really shine.
Then you have his weakness (the Serpents of Yig)... and by god will you hate this guy. His 3 health means that, unless you have Shrivelling5, it will take 2 shots to kill at least. He is difficult for you to deal with without big spells, his damage is pretty high, and he seals the token. He's worse than the Silver Twilight Acolyte, which is one of the worst weaknesses you can draw, and adding spiky-weaknesses to a spiky-class is never great. Every now and again, you will draw the Serpents in turn 1-3, before you can find your Shriveling or Mists, and it can be crippling.
So you have:
- Bad statline (possibly missing a point)
- No non-purple blessed cards released or announced yet
- Niche OPG and signature card
- Terrible weakness
- Better options available
So where does this leave you? Well, his one saving grace is the +5 XP he gets at start (or in standalone). This is meant to make up for all of the above. You have lots of options here, but they tend to fall on one of the following lines:
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(1) is to jump-start whatever build you were planning on playing. (eg, upgraded Shrivellings, Spirit Atheme). This is the approach taken in this solo deck here (https://arkhamdb.com/decklist/view/5564/solo-mateo-cheats-his-way-through-forgotten-age-1.0). This is probably the "best" approach, although if you were looking for the best, why did you pick Mateo?
- (2) is to go for something kooky, that you wouldn't normally plan to afford, like Seal of the Elder Sign, Song of the Dead or Blood Pact, straight-away. This does allow you to explore a new direction, as Mystics normally are tight on XP, and need everything for the basics (Shrivelling + friends). This is the approach taken here (https://arkhamdb.com/decklist/view/5655/the-mostly-holy-father-a-k-a-miracle-mateo-1.0). This is probably the more "fun" approach, just ensure you still have enough game-plan to achieve what you need to. Spending all the XP on the Seal, could also be a little spiky - you might never draw it.
The impact of this XP boost can be high, especially in the first 1 or 2 scenarios, although towards the end of the campaign you're likely going to notice it less.
Overall, having played the Father in a few campaigns now, I've found him to be weak and a bit boring. I'd like to see him have many more cross-colour Blessed cards to open up his options before I'd want to play him again on Hard.